http://www.dailymail.co.uk/health/article-1321434/Stem-cell-jab-end-need-hip-replacements-repairing-damaged-joints.html
This maybe a major breakthrough for a potential treatment of Osteoarthritis. If successful, we will be able to treat Osteoarthritis with an injection of stem cells instead of joint replacement surgery.
There have been ongoing attempts to regenerate cartilage but it is difficult to recreate the natural structure of cartilage in the lab. Hopefully, embryonic stem cells will make that possible.
Meanwhile there are some voo-doo remedies sold by some famous 'arthritis experts'...and I quote one here - "At our center, we are using autologous (a patient’s own stem cells) stem cell concentrates to regionally treat osteoarthritis of the knee and hip. So far, our data looks promising." Beware of these claims. They are not standardized, not approved and not paid for by insurance. And they don't work.
Sunday, October 24, 2010
Tuesday, October 12, 2010
Arthritis: It's Only Going to Get Worse
http://www.hcplive.com/articles/Arthritis-Its-Only-Going-to-Get-Worse?utm_source=Listrak&utm_medium=Email&utm_term=http%3a%2f%2fwww.hcplive.com%2farticles%2fArthritis-Its-Only-Going-to-Get-Worse&utm_campaign=Rheumatology+eDigest%3a+Arthritis+-+It%27s+Only+Going+to+Get+Worse
There won't be enough Rheumatologists to take care of these patients. But if we listened to our mothers, most of the modifiable risk factors for Osteoarthritis would be taken care of: don't smoke, don't skip school, don't be lazy and don't get fat.
It is remarkable that these four life-style changes can significantly reduce the risk of the four most prevalent diseases - arthritis, diabetes, high blood pressure and coronary artery disease. It is even more remarkable that a person's level of formal education is a strong determinant of the risk of developing many diseases, including: Rheumatoid Arthritis, Osteoarthritis, Back problems, High blood pressure, Heart attack, Stroke, Diabetes, Kidney diseases and certain Cancers. Studies have shown that high school graduates have a 2-4 fold decrease in risk of having these diseases compared to those with less than 8 years of education.
One large study from the UK found that the risk of dying from a heart attack more than triples, in men with a certain type of arrhythmia, depending on their education level:
http://www.nejm.org/doi/pdf/10.1056/NEJM197807132990202
There won't be enough Rheumatologists to take care of these patients. But if we listened to our mothers, most of the modifiable risk factors for Osteoarthritis would be taken care of: don't smoke, don't skip school, don't be lazy and don't get fat.
It is remarkable that these four life-style changes can significantly reduce the risk of the four most prevalent diseases - arthritis, diabetes, high blood pressure and coronary artery disease. It is even more remarkable that a person's level of formal education is a strong determinant of the risk of developing many diseases, including: Rheumatoid Arthritis, Osteoarthritis, Back problems, High blood pressure, Heart attack, Stroke, Diabetes, Kidney diseases and certain Cancers. Studies have shown that high school graduates have a 2-4 fold decrease in risk of having these diseases compared to those with less than 8 years of education.
One large study from the UK found that the risk of dying from a heart attack more than triples, in men with a certain type of arrhythmia, depending on their education level:
http://www.nejm.org/doi/pdf/10.1056/NEJM197807132990202
Monday, October 11, 2010
Eating Broccoli Could Guard Against Arthritis
http://www.sciencedaily.com/releases/2010/09/100915084504.htm
I hope this one works! My mother will not take Glucosamine/Chondroitin because she is a vegetarian.
There are many other vegetarian items that are claimed to be good for prevention/treatment of arthritic pain.
Here is a short list:
Oranges, Blueberries, Kiwis, Apples, Cherries, Parsley, Prunes, Carrots, Beans, Tomatoes, Ginger, Turmeric.
I hope this one works! My mother will not take Glucosamine/Chondroitin because she is a vegetarian.
There are many other vegetarian items that are claimed to be good for prevention/treatment of arthritic pain.
Here is a short list:
Oranges, Blueberries, Kiwis, Apples, Cherries, Parsley, Prunes, Carrots, Beans, Tomatoes, Ginger, Turmeric.
Saturday, October 2, 2010
FDA says NO to Colchicine and Tanezumab
The implications of the FDA's two far reaching actions last week can impact every doctor and patient in the world.
First, clinical trials of a drug were halted because it was "too good". A potential drug for Osteoarthritis - Tanezumab, was stopped from development because patients were doing better than expected and as a result hurting their joints with increased activity. I can tell from my own patient's experiences that it worked well. And it is not even a narcotic.
http://www.bloomberg.com/news/2010-09-29/pfizer-arthritis-drug-cut-pain-too-well-leading-to-joint-damage-in-study.html
Second, in truly spinning the wheel backwards, FDA is removing generic colchicine from the shelves to make room for branded colchicine (Colcrys). The difference in price is 10 cents per pill vs $5 per pill. Colchicine has been around for more than a few decades, in fact more than a century in some form or another. Now a drug company decides to manufacture it as a branded drug and go through FDA's approval process. How does that make the old generic drug any more dangerous? I am asking my patients to stock up on the generic while it is still around...and I am determined not prescribe Colcrys ever.
Second, in truly spinning the wheel backwards, FDA is removing generic colchicine from the shelves to make room for branded colchicine (Colcrys). The difference in price is 10 cents per pill vs $5 per pill. Colchicine has been around for more than a few decades, in fact more than a century in some form or another. Now a drug company decides to manufacture it as a branded drug and go through FDA's approval process. How does that make the old generic drug any more dangerous? I am asking my patients to stock up on the generic while it is still around...and I am determined not prescribe Colcrys ever.
I am baffled by these two announcements. What are they trying to do? Will the FDA now remove ALL pain killers - such as Morphine for being too good , and ALL unapproved old drugs - such as Aspirin for being dangerous?
Perhaps they could have approved Tanezumab with the same warning as they have on cigarettes - "Taking Tanezumab can be injurious to your health"....
Subscribe to:
Posts (Atom)